KMID : 1139220200160020115
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Journal of Exercise Rehabilitation 2020 Volume.16 No. 2 p.115 ~ p.117
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Impact of exercise on hippocampal neurogenesis in hyperglycemic diabetes
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Lee Chae-Bin
Baek Seung-Soo
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Abstract
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Hyperglycemic diabetes is a chronic metabolic disorder characterized by high level of plasma glucose. Numerous studies have shown that hyperglycemic diabetes leads to brain dysfunction including cognitive impairment and emotional disorders. This study evaluated the impact of exercise on brain dysfunction, hippocampal neurogenesis, and cognitive impairment in hyperglycemic diabetes. The present study suggests that exercise improves hyperglycemic control and prevents decline of cognition through increasing hippocampal neurogenesis. Understanding the mechanism of exercise for hippocampal neurogenesis can lead to the development of therapeutic strategies for metabolic disorders.
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KEYWORD
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Diabetes, Hyperglycemia, Neurogenesis, Cognitive impairment, Exercise
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